One in a Billion

One in a Billion Author Kathleen Gallagher
ISBN-10 9781451661323
Release 2016-04-12
Pages 256
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The breathtaking story of a young boy with a never-before-seen disease, and the doctors who take a bold step into the future of medicine to save him—based on the authors’ Pulitzer Prize–winning reporting. In this landmark medical narrative, in the tradition of The Immortal Life of Henrietta Lacks and The Spirit Catches You and You Fall Down, Pulitzer Prize–winning journalists Mark Johnson and Kathleen Gallagher chronicle the story of Nic Volker, the Wisconsin boy at the center of a daring breakthrough in medicine—a complete gene sequencing to discover the cure for an otherwise undiagnosable illness. At just two years old, Nic experienced a searing pain that signaled the awakening of a new and deadly disease, one that would hurl Nic and his family up against the limits of modern medicine. For years, through false starts and failed cures, Nic holds on to life, buoyed up by his mother’s fierce drive to get him the care he needs. But when even the world’s experts are stumped by Nic’s illness, his doctors come up with a radical, long-shot plan: a step into the unknown. The next major scientific frontier, following the completion of the Human Genome Project, was to figure out how to use our new knowledge to save lives—to bring genomic or personalized medicine into reality. It’s a quest that is undertaken by researchers around the world. But it is only when geneticist Howard Jacob hears about young Nic that the finish line finally comes into sight: It’s no longer a race to make history. It’s a race to save this boy’s life. One in a Billion is an unforgettable tale of the lives that converged to launch a medical revolution. As pioneering geneticist Mary-Claire King pronounced upon learning Nic’s story: “It was as if one had heard about Case Zero of AIDS and the cure, all at once.”



One in a Billion

One in a Billion Author Mark Johnson
ISBN-10 9781451661347
Release 2016-04-12
Pages 256
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“A riveting scientific detective story” (The Washington Post) by two Pulitzer Prize–winning journalists who chronicle a young Wisconsin boy with a never-before-seen disease and the doctors who save his life by taking a new step into the future of medicine. In this landmark medical narrative, Pulitzer Prize-winning journalists Mark Johnson and Kathleen Gallagher share the story of Nic Volker, the first patient to be saved by a bold breakthrough in medicine—a complete gene sequencing, aimed at finding the cause of an otherwise undiagnosable illness. At just two years old, Nic experienced a brief flicker of pain that signaled the awakening of a new and deadly disease, one that would hurl him and his family into a harrowing journey in search for a lifesaving cure. After his symptoms stump every practitioner, it becomes clear that Nic’s is a one in a billion case, a disease that no one has ever seen before. As Nic and his family search for answers, the scientific community is racing to bring about the next revolution in medicine—translating results from the Human Genome Project to treatments for actual patients. At the forefront is the brilliant geneticist Howard Jacob, who starts a lab at the Medical College of Wisconsin. Then Nic’s head physician reaches out to Jacob with an unprecedented of idea. A disease like Nic’s is likely due to a rare mutation: if they could sequence his genes to try to find the mutation, the boy might live. Jacob doesn’t know if he can do it; Nic’s doctors don’t know if it will even work; and no one knows what else might lie in the Pandora’s Box of Nic’s genome. But they decide to try—and in doing so, they step into a new era of medicine. One in a Billion is “a compelling story of a modern medical miracle—the first instance of personalized medicine” (Milwaukee Journal Sentinel) and the birth of a scientific revolution.



One in a Billion

One in a Billion Author Mark Johnson
ISBN-10 9781451661330
Release 2017-04-18
Pages 256
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“A riveting scientific detective story” (The Washington Post) by two Pulitzer Prize–winning journalists who chronicle a young Wisconsin boy with a never-before-seen disease and the doctors who save his life by taking a new step into the future of medicine. In this landmark medical narrative, Pulitzer Prize-winning journalists Mark Johnson and Kathleen Gallagher share the story of Nic Volker, the first patient to be saved by a bold breakthrough in medicine—a complete gene sequencing, aimed at finding the cause of an otherwise undiagnosable illness. At just two years old, Nic experienced a brief flicker of pain that signaled the awakening of a new and deadly disease, one that would hurl him and his family into a harrowing journey in search for a lifesaving cure. After his symptoms stump every practitioner, it becomes clear that Nic’s is a one in a billion case, a disease that no one has ever seen before. As Nic and his family search for answers, the scientific community is racing to bring about the next revolution in medicine—translating results from the Human Genome Project to treatments for actual patients. At the forefront is the brilliant geneticist Howard Jacob, who starts a lab at the Medical College of Wisconsin. Then Nic’s head physician reaches out to Jacob with an unprecedented of idea. A disease like Nic’s is likely due to a rare mutation: if they could sequence his genes to try to find the mutation, the boy might live. Jacob doesn’t know if he can do it; Nic’s doctors don’t know if it will even work; and no one knows what else might lie in the Pandora’s Box of Nic’s genome. But they decide to try—and in doing so, they step into a new era of medicine. One in a Billion is “a compelling story of a modern medical miracle—the first instance of personalized medicine” (Milwaukee Journal Sentinel) and the birth of a scientific revolution.



One In A Billion

One In A Billion Author Kai Chen
ISBN-10 145206069X
Release 2007-01-10
Pages 360
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Kai and his mother were sitting on an Air China 747 in San Francisco International Airport, waiting impatiently for take-off. Kai’s father had passed away a year before in the spring of 1988. He was taking his mother home to visit his elder brother in China. The take-off had been delayed because one of the Chinese passengers failed to show up even though he had already checked his luggage. He had decided to remain in the US illegally. This incident took Kai back in time to his own painful and courageous decisions. .... A 12 year old Kai was sitting on the train waiting to leave Beijing for Manchuria. Young Kai was confused about why he was leaving, not knowing he and his brothers were being forced to join their exiled parents in the small city of Tonghua. He had spent the past five years with an abusive grandmother and Big Brother in Beijing. Life in Tonghua wasn’t any easier for Kai who grew into a teenager with a different accent and a unique physical appearance - 6’7” by the age 15. But the most mind-boggling torment for Kai and his family was still to come. In 1966, the Cultural Revolution began. With half of his relatives in Taiwan, Kai and his family endured political persecution and discrimination. He and his brothers were again forced to leave the city to go to the countryside. Kai set out to overcome these obstacles. He used his basketball skills to land a job in a Liuhe grain depot while playing for the depot’s team. Soon after, with China’s return to professional sports, two basketball coaches from the National Sports and Athletics Commission recruited him for the National Basketball Team’s training camp in Beijing. At the camp, Kai met his best friend Xiao, a track team member, who was later expelled because his father had worked for Kuomintang’s army. Kai remained a little longer and then was also expelled for the similar reason. Determined not to return to the isolation of the small town factory, he escaped to Canton. He was caught and then forced back to Beijing, placed in solitary confinement and put under investigation. The authorities suspected him of trying to defect to Hong Kong. Little do they understand, his goal was not to escape the country, but to escape the shackles of the Big Family, that undefined “everyone” that represents generations of tradition. He was nevertheless escorted back to the Liuhe grain depot. After yet another attempt to escape, Kai was drafted by the Shenyang army team and sent to a combat unit for reeducation. The harsh conditions weakened him and, near collapse, he learned that Xiao had died, alone and in desperation. Kai was hospitalized. Struggling to pick himself up and begin again, Kai returned to the team and worked on his game. He joined the country’s top military team - the August 1st Team - and made his first trip abroad, defying the prediction that he would never be allowed to represent China abroad because he had relatives in Taiwan. He helped his team win several national titles. Yet, the National Team still rejected him. While on the August 1st Team, Kai witnessed various traps the Big Family set to control individuals. Before long he found himself at the first Tiananmen Square Incident in 1976 and was punished by the authorities. Not to be denied, Kai became the best forward in the country. Remaining an outsider, he soared to win the most important game of his life. He was unanimously selected by the recruiters for the National Team in 1978 for China’s first entry in the World Basketball Championships and the tour of USA. He had the last laugh as he had promised to Xiao and to himself - he defeated the Big Family. Yet, the struggle did not end. Searching for happiness, Kai had his first sexual encounter with a Chinese volleyball player. He retired at the peak of his professional career. He entered college and met an American exchange student. He finally tasted true happiness. They married and he left for America. .... Back in 1989, Kai again stepped into Tiananmen Square, amid a student pr



Social Photography

Social Photography Author Daniela Bowker
ISBN-10 9781781571774
Release 2014-06-02
Pages 160
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Hot photo apps come and go, but the practice of shooting and sharing is universal and is now a fundamental part of the way that we communicate with each other. Photos aren’t printed on paper anymore – they are displayed on screens; and everywhere they are shown, the viewer is invited to like or share. Social Photography will show you how to create photos that will be clicked on, liked, shared, and – if you want – go viral. A must-read for anyone who takes their online presence seriously, this book will show you how to give your photos a fresh look, give you hundreds of posing and shooting ideas, and let you share your life’s most exciting moments wider than ever before.



A Billion Jokes

A Billion Jokes Author Peter Serafinowicz
ISBN-10 9781447237754
Release 2012-11-08
Pages 320
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'Comedy genius' David Walliams 'It's funny, but Peter Serafinowicz is the kind of funny person that funny people find funny' Simon Pegg 'Peter Serafinowicz is one of the funniest women in the world' Derren Brown Jokes include: 'I like to put my Shredded Wheat through my own shredder, just to be on the safe side.' 'Dear Sir/Madam, Your transgender operation was a partial success.' 'Float like an octopus, sting like a clock' - Muhammad Dali 'Jeremy Clarkson is like Marmite. Revolting.' 'I used to find buying books from Amazon slow and inconvenient, until one day the receptionist suggested I use their website.'



A Billion to One

A Billion to One Author John Herzog
ISBN-10 0964263025
Release 2017-05-01
Pages
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Legendary Nasdaq market-maker John E. Herzog shares the story of his business in this unabashed tribute to his partners, family, and friends.Inspired by his father, Herzog's route to building a securities trading behemoth starts modestly, when his grandfather, walking the teeming streets of Manhattan's Lower East Side, begins trading currencies. His father, Robert, joins these walks and learns how to earn a modest "spread" changing notes and handling remittances for newly-arrived emigres. The Herzogs' stock in trade is fair dealing, and as the decades roll by, we see that never changes.Robert apprentices at a bank where his aptitude for figures and entrepreneurial yearnings lead him to abandon a dependable $50 monthly wage for his first partnership. Rapid changes make him a sole proprietor very quickly, beginning a struggle just to stay in business. The family firm has survived more than prospered in 1959, when John accepts his father's invitation to join the four others that comprise the staff of Herzog & Co. Opportunity is elusive as he struggles to find business and develop a specialty. On a typical day, the firm makes only four or five trades!John's most significant deal is convincing two similarly principled brothers to put their doughnut business on hold while developing their trading careers at Herzog & Co. The very talented Irwin and Buzzy Geduld work with John to build a company with the ability and culture ideally suited to an expanding national trading opportunity. With a long list of company shareholders, the exquisitely timed sale of Herzog, Heine, Geduld to Merrill Lynch provides the ultimate reward.This intimate memoir would be more believable had it not happened on Wall Street. It's an unconventional story for that place: it's about integrity, not greed, where wrongs are quickly righted and fairness is never mistaken for generosity. For Herzog, the reward is sharing success with all who made it possible, and his story tells us how that happened.



One in a Billion

One in a Billion Author Ludan Bone
ISBN-10 9781925152012
Release 2014
Pages 142
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When Ludan Bone started making her phone calls to China in 1993 she was one woman with no contacts trying to sell an intangible, copyrighted product to an industry where royalties were alien. But over the next two decades, she built a formidable business from scratch and became the biggest player in the production music business in China. The business memoir, One in a Billion, charts Ludan’s rise from a part-time marketing manager in Sydney to the head of her own top-tier firm in Beijing with one of the biggest music libraries in the world. It follows her successes and failures, the frequent overhauls in the Chinese broadcasting industry and the practical challenges of operating in the mainland business world. To get where she is today, Ludan had to educate an entire market and convince potential clients that her high-end product would revolutionize their way of working. Production music has transformed broadcasting in China, so much so that few today could do without it. The book also gives insight into mainland culture and offers tips for would-be entrepreneurs, businesspeople in China and anybody trying to make an idea pay on the mainland. The information based on direct experience and applies to all those with a dream of taking an idea into uncharted territory. One in a Billion gives a practical and accessible insider’s look at how a new business idea was turned into a reality against the odds. Ludan’s company, Songba, has risen from obscurity to one of the leading names in professional broadcasting. This book tells the story of an individual entrepreneur and how she relied on her own wits to make her way in China. In addition, it covers three themes that not found together elsewhere but that are more important than ever: copyright, media and music in China.



Blueprint to a Billion

Blueprint to a Billion Author David G. Thomson
ISBN-10 1118040643
Release 2010-12-08
Pages 288
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Praise for BLUEPRINT TO A BILLION "A wonderful, well thought out analysis of entrepreneurship and leadership of a growth company." —Howard Lester, Chairman, Williams-Sonoma, Inc. "If you dream about growing your business to a billion, this is a fascinating down-to-earth study that you must read. Apply the seven essential principles to your business and you are off and running. Learn about strategy, growth, leadership, team building, and a whole lot more." —Joe Scarlett, Chairman of the Board, Tractor Supply Company "Blueprint to a Billion is a well-researched and thoughtfully written book that quantifies the growth pattern of America's highest growth companies." —Professor John Quelch, Senior Associate Dean, Harvard Business School "Eighty percent of the top-performing stocks in the last twenty years were small entrepreneurial companies that had an IPO in the prior eight years. Blueprint to a Billion tells you the seven key things these innovators did in common to become America's greatest growth companies." —William J. O'Neil, Chairman and Founder Investor's Business Daily, www.investors.com "Thomson has written a masterful work that will catalyze, empower, inspire, motivate, and illuminate entrepreneurs, investors, and policymakers. The world needs this book and will profit from it in manifold ways." —David M. Darst, Managing Director, Individual Investor Group Chief Investment Strategist, Morgan Stanley



One in a Billion

One in a Billion Author Sharlee Mullins Glenn
ISBN-10 1929281064
Release 2000-01-01
Pages 32
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This story portrays a discovery we all must make, that being one of many doesn't diminish who we are. Each of us in unique in all the world.



One Billion Customers

One Billion Customers Author James McGregor
ISBN-10 9780743282451
Release 2005-10-19
Pages 336
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It is well known that with a population of 1.3 billion people, China's market is moving quickly toward surpassing those of North America and Europe combined. Companies from the United States and around the globe are flocking there to buy, sell, manufacture, and create new products. But as former Wall Street Journal China bureau chief turned successful corporate executive James McGregor explains, business in China is conducted with a lot of subterfuge -- nothing is as it seems and nothing about doing business in China is easy. Destined to become the bible for business people in China, One Billion Customers shows how to navigate the often treacherous waters of Chinese deal-making. Brilliantly written by an author who has lived in China for nearly two decades, the book reveals indispensable, street-smart strategies, tactics, and lessons for succeeding in the world's fastest growing consumer market. Foreign companies rightly fear that Chinese partners, customers, or suppliers will steal their technology or trade secrets or simply pick their pockets. Testy relations between China's Communist leaders and the United States and other democracies can trap foreign companies in a political crossfire. McGregor has seen or experienced it all, and now he shares his insights into how China really works. One Billion Customers maximizes the expansive knowledge of a respected journalist, well-known businessman, and ultimate China insider, offering compelling narratives of personalities, business deals, and lessons learned -- from Morgan Stanley's creation of a joint-venture Chinese investment bank to the pleasure dome of a smuggler whose $6 billion operation demonstrates how corruption greases the wheels of Chinese commerce. With nearly 100 strategies for conducting business in China, this unprecedented account combines practical lessons with the story of China's remarkable rise to power.



One in a Billion

One in a Billion Author Sandy Thompson
ISBN-10 1576872963
Release 2006
Pages 143
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China is a land of billions. A billion people, billions of dollars in spending power, and billions of hopes and dreams. Now, at the dawn of a new millennium, China is poised to be one of the greatest social and economic forces in world history. What few realize, though, is that over 95 percent of China's growth over the last two years has been generated by domestic demand. For brands to gain a foothold in this rapidly expanding economy, dollars are not enough. Nor is information, such as that gleaned from focus groups and traditional market research. To reach the 1.3 billion potential consumers in China, you need to understand: understand the people, their lives and motivations, ambitions and desires. And to move past knowledge to understanding, you need to Xplore.



A Billion to One

A Billion to One Author Gene Ayres
ISBN-10 1935444069
Release 2009-02
Pages 264
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Seattle author Gene Ayres recounts his extended stay in China.



One Billion Hungry

One Billion Hungry Author Gordon Conway
ISBN-10 9780801466083
Release 2012-10-16
Pages 456
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Hunger is a daily reality for a billion people. More than six decades after the technological discoveries that led to the Green Revolution aimed at ending world hunger, regular food shortages, malnutrition, and poverty still plague vast swaths of the world. And with increasing food prices, climate change, resource inequality, and an ever-increasing global population, the future holds further challenges. In One Billion Hungry, Sir Gordon Conway, one of the world's foremost experts on global food needs, explains the many interrelated issues critical to our global food supply from the science of agricultural advances to the politics of food security. He expands the discussion begun in his influential The Doubly Green Revolution: Food for All in the Twenty-First Century, emphasizing the essential combination of increased food production, environmental stability, and poverty reduction necessary to end endemic hunger on our planet. Beginning with a definition of hunger and how it is calculated, and moving through issues topically both detailed and comprehensive, each chapter focuses on specific challenges and solutions, ranging in scope from the farmer's daily life to the global movement of food, money, and ideas. Drawing on the latest scientific research and the results of projects around the world, Conway addresses the concepts and realities of our global food needs: the legacy of the Green Revolution; the impact of market forces on food availability; the promise and perils of genetically modified foods; agricultural innovation in regard to crops, livestock, pest control, soil, and water; and the need to both adapt to and slow the rate of climate change. One Billion Hungry will be welcomed by all readers seeking a multifacted understanding of our global food supply, food security, international agricultural development, and sustainability.



One in a Billion

One in a Billion Author Beth Kery
ISBN-10 9781459234956
Release 2012-08-01
Pages 224
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The discovery that corporate mogul Lincoln DuBois had left her half his company rocked Deidre Kavanaugh's world. After all, she'd only just learned that the billionaire could be her real father. And with his right-hand man, Nick Malone, up in arms, claiming her share of the inheritance wouldn't be easy. Charismatic tycoon Nick Malone had his doubts about Deidre's paternity claim, but it was hard to remain aloof when all he wanted to do was kiss her! Nick couldn't seem to stop wanting to protect the rebellious beauty—or silence the desire to make her his own. And if her claim was true, Nick could lose half his inheritance. So why was he focusing on what he could gain…a lifetime of love with the woman of his dreams?



A Billion Reasons Why

A Billion Reasons Why Author Kristin Billerbeck
ISBN-10 9781401685362
Release 2011-01-31
Pages 320
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There are a billion reasons Kate should marry her current boyfriend. Will she trade them all to be madly in love? Katie McKenna leads a perfect life. She has a fulfilling job, a cute apartment, and a wedding to plan with her soon-to-be fiancé, Dexter. She can think of a billion reasons why she should marry Dexter. He’s everything she wants in a husband. And then in walks Luc DeForges, her bold, breathtaking ex-boyfriend. Only now he’s a millionaire. And he wants her to go home to New Orleans to sing for a friend’s wedding. As his date. But Katie made up her mind about Luc eight years ago, when she fled their hometown after a very public breakup. Yet there’s still a magnetism between them she can’t deny. Katie thought her predictable relationship with Dexter would be the bedrock of a lasing, Christian marriage. But what if there’s more? What if God’s desire for her is a heart full of life? And what if that’s what Luc has offered all along? "Katie and Luc dance off the pages of this book, making you fall in love with them and New Orleans. Full of surprises and romance." —Carolyne Aarsen, author of The Baby Promise



A Billion Days Of Earth

A Billion Days Of Earth Author Doris Piserchia
ISBN-10 9780575133587
Release 2015-04-30
Pages 200
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The Earth teemed with life of all kinds, and many besides man had intelligence and the gift of speech. But chaos ruled. And violence. And despair. Then, in the Valley of the Dead, Sheen first entered the world, and all of the life would bend to the might of the Supreme One before the final push to the stars.